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    Identifying Prognostic Biomarkers for Amyotrophic Lateral Sclerosis

    Using multiplex biomarker analysis, researchers at Penn State University aim to define a panel of prognostic ALS markers.  This study shows the most meaningful results were obtained when combining biomarkers from CSF and plasma, rather than focusing on a single parameter. The combined plasma and CSF panel consists of six markers and accurately predicted the […]

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    Recorded Webinar: Quantitative Profiling of the Intrinsic Pathway of Apoptosis in Tumor Tissue using Myriad RBM’s Multiplex ApoptosisMAP™

    If you were unable to attend the webinar or would like to view the webinar again, a recorded version is now available for your convenience. View Recorded Webinar Learn about the creation of Myriad RBM’s fully validated, quantitative ApoptosisMAP and its application in cancer therapy research. The webinar highlights the main features of the service, […]

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    Using Renal Biomarkers to Advance Drug and Diagnostic Development in Kidney Disease

    Read this ebook, published by FierceBiotech, to learn how researchers are using new, more sensitive biomarkers to develop drugs and diagnostics in kidney disease. http://www.fiercebiomarkers.com/offer/renal_biomarkers

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    The Need for Additional Translational Biomarkers

    The authors of this paper review the various methods of safety biomarker discovery and development, and challenge researchers to advance the use of safety biomarkers that are indicative of drug-induced toxicity. This type of research typically spans both preclinical and clinical development programs. Having the ability to identify translational safety biomarkers on the same technology […]

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    Blood-based Biomarkers of Alzheimer’s disease

    As we continue to develop a better understanding of the underlying biology for neurological diseases such as Alzheimer’s, researchers are seeking biomarkers that may help in numerous ways. From early diagnosis or disease progression, to surrogate efficacy markers for treatments, biomarkers may be the key to better studying these diseases. The challenge is determining which […]

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    Cancer Biomarkers – Historically undervalued but it’s time for a change

    Tumor-Biomarker Diagnostics: More and more experts are realizing the value of biomarkers in cancer research, not only to monitor tumor progression, but also to guide the treatment of patients.  Understanding these factors has the potential to save tremendous amounts of money for researchers in clinical trials and could even influence insurance reimbursement plans for those […]

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    Markers of Neurodegeneration in Multiple Sclerosis

    A recent study has identified the increased presence of neurofilament subunits (NFL) in the serum and cerebrospinal fluid of patients with multiple sclerosis (MS). The research, published in the Journal of Neuroimmunology, suggests that NFL may induce an immune response and represent and early marker of axonal damage. The results support many previous findings that […]

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    Evidence Supporting another Amyloid Biomarker of Alzheimer’s

    Researchers at the UC Davis Alzheimer’s Disease Center have identified the protein amylin as another possible biomarker of AD. Amylin is a protein that is related to amyloid beta, a known marker of AD. Build up of amylin oligomers in patients at risk for diabetes creates a cytotoxic environment which damages the cells in the […]

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    How to use multiplexed immunoassays in inflammatory diseases

    Chronic inflammatory processes are associated with a remarkable range of human diseases including numerous cardiovascular, pulmonary, neurodegenerative, and autoimmune disorders. Advances in our understanding of inflammatory biomarkers and their role in disease offer tremendous clinical value. Myriad RBM’s multi-analyte profiling (MAP) technology provides comprehensive, quantitative and sensitive measurement of dozens of protein biomarkers involved in […]

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    Biomarker Reliability and Disease Characteristics

    Proper study design is one of the most important aspects of successful biomarker discovery and that includes both a thorough understanding of the disease population and which statistical tools to use. New research from Arizona State University examines how the predictive reliability of statistical tests relies not only on the choice of the test (clearly) […]

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