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    New Blood-Based Biomarker Assay for the Early Detection of Kidney Cancer

    Researchers identified a 3-biomarker immunoassay, measuring NNMT, LCP1, and NM23A, that successfully distinguishes healthy patients from those with renal cell carcinoma (RCC). If their results can be validated, physicians would have an unprecedented tool for the early detection and subsequent treatment of this silent and deadly disease.

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    Blood-Based Biomarkers Included in Scientific American Timeline of Schizophrenia Research

    Less than two hundred years ago schizophrenia emerged from a tangle of mental disorders known simply as madness. Today its diagnosis remains shrouded in ambiguity. Psychiatrists may discover that this disorder is not a single syndrome after all but a bundle of overlapping conditions. The highlighted research is from Myriad RBM’s collaboration with Sabine Bahn’s […]

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    Molecular Sex Differences in Human Serum

    A recent article featuring Myriad RBM’s services was published in PLoS ONE by a group of researchers investigating the differences in biomarker profiles between men and women. The group measured 174 proteins across nine independent groups, with 196 males and 196 females. As would be expected, clusters of molecules with distinct biological roles, such as […]

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    Levels of an Inflammatory Marker Linked to Depression

    There is mounting evidence that systemic inflammation is involved in depression and now a recent article in JAMA Psychiatry supports this hypothesis. Danish researchers looked at data from two broad population studies with a total of more than 73,000 individuals and found that elevated levels of CRP were commonly found in depressed patients. While the […]

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    Grant Funding Awarded to Mayo Clinic for Gut Biomarker Research

    The Grand Challenges in Global Health Initiative, an organization launched by the Bill & Melinda Gates Foundation, last year issued a challenge to “Discover Biomarkers of Health and Disease“, specifically in two areas: Biomarkers of Tuberculosis and Biomarkers of Gut Function. The goal of this challenge was to discover validated biomarkers that could improve the […]

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    Myriad Announces Diabetes Collaboration with Sanofi

    As a major participant in the largest protein biomarker study of its kind, Myriad RBM will analyze more than 8,000 samples for Sanofi Aventis’ Outcome Reduction with Initial Glargine Intervention (ORIGIN) project, a pre- and early diabetes clinical study. The goal of the collaboration is to identify biomarker profiles that optimize treatment and improve care […]

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    Exciting New Research Forthcoming for Biomarkers of Lung Disease

    Dr. Ivan O Rosas, a faculty member in the Division of Pulmonary and Critical Care, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School and Director of the Pulmonary Fibrosis Program at the Lovelace Respiratory Research Institute has published several recent papers investigating lung diseases, including a 2011 paper in the New England Journal […]

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    Biomarkers in Drug Development: We’re entering into an exciting era.

    Today, nearly every drug development program has a biomarker discovery project with which it is associated. In just the last five years, this has become the standard operation rather than the exception. Why has this happened so quickly? It was because we could. Technologies perfected in the 90s and early this young century have provided […]

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    Considerations for Biomarker Research – How to Choose the Right Assays and Technology?

    Many questions need to be answered in the process of designing a research study, even more so when biomarkers are going to be a component. While biomarkers can add a lot of information, e.g. insight into how subjects are responding to treatment or patient stratification, it is worth considering up front exactly what you need […]

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    Biomarkers Play an Increasingly Large Role in Cancer Research

    Oncology research and personalized cancer therapies will (and do) benefit greatly from the use of biomarkers. By illuminating genetic profiles and molecular pathways, biomarkers and biomarker signatures offer hope for truly personalized medicine in a field where the disease is extremely complex. Combinations of biomarkers may be used to direct therapy and monitor disease progression. […]

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