Biomarker Details - Myriad RBM

Monokine Induced by Gamma Interferon (MIG)

Monokine Induced by Gamma Interferon (MIG; CXCL9) is a small cytokine belonging to the family of CXC chemokines. MIG is a T-cell chemoattractant whose expression is induced by interferon gamma. MIG production has proven to be a sensitive measure of antigen-specific IFN production. It affects the growth, movement, and activation state of cells that participate in immune and inflammatory response. MIG is chemotactic for activated T-cells and binds to CXCR3.

Swiss-Prot Accession Number: Q07325


The Tyrosine Kinase Inhibitors Imatinib and Dasatinib Reduce Myeloid Suppressor Cells and Release Effector Lymphocyte Responses. (2015) Christiansson L, Soderlund S, Mangsbo SM, Hjorth-Hansen H, Höglund M, Markevarn B, Richter J, Stenke L, Mustjoki S, Loskog A, Olsson-Stromberg U. Mol Cancer Ther. 2015 Mar 11. pii: molcanther.0849.2014. [Epub ahead of print]

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