Matrix Metalloproteinase-10 (MMP-10), also known as stromelysin 2, degrades proteoglycans and fibronectin. MMP-10 has been linked to cancer stem cell vitality and metastasis. MMP-10 is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes such as arthritis.
Swiss-Prot Accession Number: P09238
Publications Multivariate Protein Signatures of Pre-Clinical Alzheimer's Disease in the Alzheimer's Disease Neuroimaging Initiative (ADNI) Plasma Proteome Dataset
(2012) Johnstone D, Milward EA, Berretta R, Moscato P PLoS One. 2012;7(4):e34341
Multiplexed Immunoassay Panel Identifies Novel CSF Biomarkers for Alzheimer's Disease Diagnosis and Prognosis
(2011) Craig-Schapiro R, Kuhn M, Xiong C, Pickering EH, Liu J, Misko TP, Perrin RJ, Bales KR, Soares H, Fagan AM, Holtzman DM PLoS One. 2011 Apr 19;6(4):e18850
Matrix metalloproteinases during and outside of migraine attacks without aura.
(2009) Ashina M, Tvedskov JF, Lipka K, Bilello J, Penkowa M, Olesen J Cephalalgia 30: 303-310.