Inflammation and Immune Response - Myriad RBM


Inflammation and Immune Response


The Pharmacodynamic Impact of Apremilast, an Oral Phosphodiesterase 4 Inhibitor, on Circulating Levels of Inflammatory Biomarkers in Patients with Psoriatic Arthritis: Substudy Results From a Phase 3, Randomized, Placebo-Controlled Trial (PALACE 1). (2015) Schafer P, Chen P, Fang L, Wang A, Chopra R. J Immunol Res 2015 Jan 10 [Epub ahead of print]

Anti-inflammatory T-cell shift in neuropathic pain. (2015) Luchting B, Rachinger-Adam B, Heyn J, Hinske L, Kreth S, Azad S. J Neuroinflammation. 2015 Jan 21;12(1):12. [Epub ahead of print]

Acute and chronic plasma metabolomic and liver transcriptomic stress effects in a mouse model with features of post-traumatic stress disorder. (2015) Gautam A, D'Arpa P, Donohue DE, Muhie S, Chakraborty N, Luke BT, Grapov D, Carroll EE, Meyerhoff JL, Hammamieh R, Jett M. PLoS One. 2015 Jan 28;10(1):e0117092. doi: 10.1371/journal.pone.0117092. eCollection 2015.

Evaluation of thymosin alpha 1 (Ta1) in nonclinical models of the immune-suppressing indications melanoma and sepsis. (2015) King RS, Tuthill C. Expert Opin Biol Ther. 2015 Feb 2:1-9. [Epub ahead of print]

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Effect of ozone exposure and infection on bronchoalveolar lavage: Sex differences in response patterns (2014) Mikerov AN, Phelps DS, Gan X, Umstead TM, Haque R, Wang G, Floros J Toxicol Lett. 2014 Apr 21. pii: S0378-4274(14)00167-2

Targeting glycosaminoglycans in the lung by an engineered CXCL8 as a novel therapeutic approach to lung inflammation (2014) Adage T, Konya V, Weber C, Strutzmann E, Fuchs T, Zankl C, Gerlza T, Jeremic D, Heinemann A, Kungl AJ. Eur J Pharmacol. 2014 Dec 29. pii: S0014-2999(14)00889-9. doi: 10.1016/j.ejphar.2014.12.019. [Epub ahead of print]

Basal inflammation and innate immune response in chronic multisite musculoskeletal pain. (2014) Generaal E, Vogelzangs N, Macfarlane GJ, Geenen R, Smit JH, Dekker J, Penninx BW. Pain. 2014 Aug;155(8):1605-12. doi: 10.1016/j.pain.2014.05.007. Epub 2014 May 9.
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Reduction of pro-inflammatory cytokines in rats following 7-day oral supplementation with a proprietary eggshell membrane-derived product (2014) Ruff KJ, DeVore DP Modern Research in Inflammation, 3, 19-25

Nonclinical Safety Profile of BMS-986001, a Nucleoside Transcriptase Inhibitor for Combination Retroviral Therapy (2014) Mausumee G, Frank S, Shawn C, Dara H, Zhao Y, Soleil PM, Sanderson TP, Michael G, Marc D Int J Toxicol. 2014 May 20;33(3):204-218

Predicting therapeutic efficacy of intravenous immunoglobulin (IVIG) in individual patients with relapsing remitting multiple sclerosis (RRMS) by functional genomics (2014) Thomas Berger, Christian Jacob, Judith Haas, Gerhard Ransmayr, Michael Guger, Uwe K. Zettl, Franziska Di Pauli, Birgit Taumberger, Stefan Wietek, Stefan Meuer, Markus Reindl, Thomas Giese Journal of Neuroimmunology DOI: 10.1016/j.jneuroim.2014.10.001

A prospective assessment of the effect of aminophylline therapy on urine output and inflammation in critically ill children (2014) Tamburro RF, Thomas NJ, Ceneviva GD, Dettorre MD, Brummel GL, Lucking SE Front. Pediatr. 2:59

Pharmacologic inhibition of S-nitrosoglutathione reductase protects against experimental asthma in BALB/c mice through attenuation of both bronchoconstriction and inflammation (2014) Blonder JP, Mutka SC, Sun X, Qiu J, Green LH, Mehra NK, Boyanapalli R, Suniga M, Look K, Delany C, Richards JP, Looker D, Scoggin C, Rosenthal GJ BMC Pulm Med. 2014 Jan 10;14(1):3

Exploring effects of a natural combination medicine on exercise-induced inflammatory immune response: A double-blind RCT (2014) Pilat C, Frech T, Wagner A, Krüger K, Hillebrecht A, Pons-Kühnemann J, Scheibelhut C, Bödeker RH, Mooren FC Scand J Med Sci Sports. 2014 Jun 12

Functional Analysis via Standardized Whole-Blood Stimulation Systems Defines the Boundaries of a Healthy Immune Response to Complex Stimuli (2014) Duffy D, Rouilly V, Libri V, Hasan M, Beitz B, David M, Urrutia A, Bisiaux A, LaBrie ST, Dubois A, Boneca IG, Delval C, Thomas S, Rogge L, Schmolz M, Quintana-Murci L, Albert ML Immunity Volume 40, Issue 3, 20 March 2014, Pages 436–450

Altered Macrophage-Phenotype Transition Impairs Skeletal Muscle Regeneration (2014) Wang H, Melton D, Porter L, Sarwar ZU, McManus LM, Shireman PK Am J Pathol. 2014 Feb 10. pii: S0002-9440(14)00025-X

Truncated CXCL10 is associated with failure to achieve spontaneous clearance of acute hepatitis C infection (2014) Riva A, Laird M, Casrouge A, Ambrozaitis A, Williams R, Naoumov NV, Albert ML, Chokshi S Hepatology. 2014 Mar 26

An integrated omics analysis: impact of microgravity on host response to lipopolysaccharide in vitro (2014) Chakraborty N, Gautam A, Muhie S, Miller SA, Jett M, Hammamieh R. BMC Genomics 2014 Aug 7;15(1):659. [Epub ahead of print]

Combined Inflammatory and Metabolic Defects Reflected by Reduced Serum Protein Levels in Patients with Buruli Ulcer Disease (2014) Phillips RO, Sarfo FS, Landier J, Oldenburg R, Frimpong M, Wansbrough-Jones M, Abass K, Thompson W, Forson M, Fontanet A, Niang F, Demangel C PLoS Negl Trop Dis. 2014 Apr 10;8(4):e2786

Citrus limonin glucoside supplementation decreased biomarkers of liver disease and inflammation in overweight human adults. (2014) Kelley, Darshan S., Adkins, Yuriko C., Zunino, Susan J., Woodhouse, Leslie R., Bonnel, Ellen L., Breksa III, Andrew P., Manners, Gary D., Mackey, Bruce E. Journal of Functional Foods
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Multi-analyte profile analysis of plasma immune proteins: altered expression of peripheral immune factors is associated with neuropsychiatric symptom severity in adults with and without chronic hepatitis C virus infection (2013) Huckans M, Fuller BE, Olavarria H, Sasaki AW, Chang M, Flora KD, Kolessar M, Kriz D, Anderson JR, Vandenbark AA, Loftis JM Brain and Behavior

The Ultra-Potent and Selective TLR8 Agonist VTX-294 Activates Human Newborn and Adult Leukocytes (2013) Dowling DJ, Tan Z, Prokopowicz ZM, Palmer CD, Matthews MA, Dietsch GN, Hershberg RM, Levy O PLoS One. 2013;8(3):e58164
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Application of meta-analysis methods for identifying proteomic expression level differences (2013) Amess B, Kluge W, Schwarz E, Haenisch F, Alsaif M, Yolken RH, Leweke FM, Guest PC, Bahn S. Proteomics. 2013 Apr 14.

Global chemokine expression in systemic sclerosis (SSc): CCL19 expression correlates with vascular inflammation in SSc skin (2013) Mathes AL, Christmann RB, Stifano G, Affandi AJ, Radstake TR, Farina GA, Padilla C, McLaughlin S, Lafyatis R Ann Rheum Dis. 2013 Jul 19

Suppression of Inflammation with Conditional Deletion of the Prostaglandin E2 EP2 Receptor in Macrophages and Brain Microglia (2013) Johansson JU, Pradhan S, Lokteva LA, Woodling NS, Ko N, Brown HD, Wang Q, Loh C, Cekanaviciute E, Buckwalter M, Manning-Bog AB, Andreasson KI J Neurosci. 2013 Oct 2;33(40):16016-16032

Production of LPS-induced inflammatory mediators in murine peritoneal macrophages: neocuproine as a broad inhibitor and ATP7A as a selective regulator (2013) Patel OV, Wilson WB, Qin Z BioMetals, April 2013

The Innate Immune Response May Be Important For Surviving Plague In Wild Gunnison's Prairie Dogs (2013) Busch JD, Van Andel R, Stone NE, Cobble KR, Nottingham R, Lee J, VerSteeg M, Corcoran J, Cordova J, Van Pelt W, Shuey MM, Foster JT, Schupp JM, Beckstrom-Sternberg S, Beckstrom-Sternberg J, Keim P, Smith S, Rodriguez-Ramos J, Williamson JL, Rocke TE, Wagner DM Journal of Wildlife Diseases 2013 49:4, 920-931

Development of a small animal peripheral challenge model of Japanese encephalitis virus using interferon deficient AG129 mice and the SA14-14-2 vaccine virus strain (2013) Calvert AE, Dixon KL, Delorey MJ, Blair CD, Roehrig JT Vaccine. 2013 Nov 17. pii: S0264-410X(13)01533-8

Distinct Roles For Hepcidin and Interleukin 6 In The Recovery From Anemia Following Administration Of Heat-Killed Brucella Abortus (2013) Gardenghi S, Renaud TM, Meloni A, Casu C, Crielaard BJ, Bystrom LM, Greenberg-Kushnir N, Sasu BJ, Cooke KS, Rivella S Blood. 2013 Dec 19. [Epub ahead of print]

Galectin-3 functions as an alarmin: pathogenic role for sepsis development in murine respiratory tularemia (2013) Mishra BB, Li Q, Steichen AL, Binstock BJ, Metzger DW, Teale JM, Sharma J PLoS One. 2013;8(3):e59616

Sweet Bing Cherries Lower Circulating Concentrations of Markers for Chronic Inflammatory Diseases in Healthy Humans (2013) Kelley DS, Adkins Y, Reddy A, Woodhouse LR, Mackey BE, Erickson KL J Nutr. 2013 Jan 23. [Epub ahead of print]

Transient inflammatory-like state and microbial dysbiosis are pivotal in establishment of mucosal homeostasis during colonisation of germ-free mice (2013) Aidy SE, Derrien M, Aardema R, Hooiveld G, Richards SE, Dane A, Dekker J, Vreeken R, Levenez F, Doré J, Zoetendal EG, van Baarlen P, Kleerebezem M Benef Microbes. 2013 Dec 9:1-11.

Systemic sRAGE is a Biomarker of Emphysema and Associated with AGER Genetic Variants in COPD Patients (2013) Cheng DT, Kim DK, Cockayne DA, Belousov A, Bitter H, Cho, MH, Duvoix A, Edwards LD, Lomas DA, Miller BE, Reynaert N, Tal-Singer R, Wouters E, Agusti A, Fabbri LM, Rames A, Visvanathan S, Rennard SI, Jones P, Parmar H, MacNee W, Wolff G, Silverman EK, Mayer RJ, Pillai SG, and on Behalf of the TESRA and ECLIPSE Investigators American Journal of Respiratory And Critical Care Medicine ja (2013)

The effects of vitamin A on cells of innate immunity in vitro (2013) Wojtal K, Wolfram L, Frey-Wagner I, Lang S, Scharl M, Vavricka SR, Rogler G Toxicology in Vitro,
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CXCL10 antagonism and plasma sDPPIV correlate with increasing liver disease in chronic HCV genotype 4 infected patients (2013) Ragab D, Laird M, Duffy D, Casrouge A, Mamdouh R, Abass A, Shenawy DE, Shebl AM, Elkashef WF, Zalata KR, Kamal M, Esmat G, Bonnard P, Fontanet A, Rafik M, Albert ML Cytokine. 2013 May 7. pii: S1043-4666(13)00181-6

Seasonal H3N2 influenza A virus fails to enhance Staphylococcus aureus co-infection in a non-human primate respiratory tract infection model (2013) Kobayashi SD, Olsen RJ, Lacasse RA, Safronetz D, Ashraf M, Porter AR, Braughton KR, Feldmann F, Clifton DR, Kash JC, Bailey JR, Gardner DJ, Otto M, Brining DL, Kreiswirth BN, Taubenberger JK, Parnell MJ, Feldmann H, Musser JM, Deleo FR Virulence. 2013 Oct 8;4(8). [Epub ahead of print]

The ABCs of viral hepatitis that define biomarker signatures of acute viral hepatitis (2013) Duffy D, Saleh R, Laird M, Soneson C, Fouler LL, El-Daly M, Casrouge A, Decalf J, Abbas A, Eldin NS, Fontes M, Hamid MA, Mohamed MK, Rafik M, Fontanet, Albert, M. L. Hepatology

Modulation of cardiometabolic pathways in skin and serum from patients with psoriasis (2013) Mehta NN, Li K, Szapary P, Krueger J, Brodmerkel C J Transl Med. 2013 Aug 22;11(1):194.

Increased accumulation of regulatory granulocytic myeloid cells in mannose receptor C type 1-deficient mice correlates with protection in a mouse model of neurocysticercosis (2013) Mishra PK, Morris EG, Garcia JA, Cardona AE, Teale JM Infect Immun. 2013 Apr;81(4):1052-63

Identification of a molecular profile associated with immune status in first onset schizophrenia patients (2013) Herberth M, Rahmoune H, Schwarz E, Koethe D, Harris LW, Kranaster L, Witt SH, Spain M, Barnes A, Schmolz M, Leweke MF, Guest PC, Bahn S Clin Schizophr Relat Psychoses. 2013 Feb 8:1-14

Protective role of Mincle in bacterial pneumonia by regulation of neutrophil mediated phagocytosis and extracellular trap formation (2013) Sharma A, Steichen AL, Jondle CN, Mishra BB, Sharma J J Infect Dis. 2013 Dec 17. [Epub ahead of print]

Preclinical Characterization of GLPG0634, a Selective Inhibitor of JAK1, for the Treatment of Inflammatory Diseases (2013) Van Rompaey L, Galien R, van der Aar EM, Clement-Lacroix P, Nelles L, Smets B, Lepescheux L, Christophe T, Conrath K, Vandeghinste N, Vayssiere B, De Vos S, Fletcher S, Brys R, van 't Klooster G, Feyen JH, Menet C J Immunol. 2013 Sep 4. [Epub ahead of print]

Suppression of soluble T cell-associated proteins by an anti-interferon-a monoclonal antibody in adult patients with dermatomyositis or polymyositis (2013) Guo X, Higgs BW, Rebelatto M, Zhu W, Greth W, Yao Y, Roskos LK, White WI Rheumatology (Oxford). 2013 Dec 19

Chikungunya Virus-associated Long-term Arthralgia: A 36-month Prospective Longitudinal Study (2013) Schilte C, Staikovsky F, Couderc T, Madec Y, Carpentier F, Kassab S, Albert ML, Lecuit M, Michault A PLoS Negl Trop Dis. 2013 Mar;7(3):e2137

CD47 fusion protein targets CD172a+ cells in Crohn’s disease and dampens the production of IL-1ß and TNF (2013) Baba N, Van VQ, Wakahara K, Rubio M, Fortin G, Panzini B, Soucy G, Wassef R, Richard C, Tamaz R, Lahaie R, Bernard EJ, Caussignac Y, Leduc R, Lougnarath R, Bergeron C, Racicot MA, Bergeron F, Panzini MA, Demetter P, Franchimont D, Schäkel K, Weckbecker G, Kolbinger F, Heusser C, Huber T, Welzenbach K, Sarfati M J Exp Med. 2013 May 13. [Epub ahead of print]

Interleukin 17F Level and Interferon Beta Response in Patients With Multiple Sclerosis (2013) Hartung HP, Steinman L, Goodin DS, Comi G, Cook S, Filippi M, O'Connor P, Jeffery DR, Kappos L, Axtell R, Knappertz V, Bogumil T, Schwenke S, Croze E, Sandbrink R, Pohl C JAMA Neurol. 2013 Aug 1;70(8):1017-21

REG3-gamma-deficient mice have altered mucus distribution and increased mucosal inflammatory responses to the microbiota and enteric pathogens in the ileum (2013) Loonen LM, Stolte EH, Jaklofsky MT, Meijerink M, Dekker J, van Baarlen P, Wells JM Mucosal Immunol. 2013 Dec 18

Preclinical Characterization of GLPG0634, a Selective Inhibitor of JAK1, for the Treatment of Inflammatory Diseases (2013) Van Rompaey L, Galien R, van der Aar EM, Clement-Lacroix P, Nelles L, Smets B, Lepescheux L, Christophe T, Conrath K, Vandeghinste N, Vayssiere B, De Vos S, Fletcher S, Brys R, van 't Klooster G, Feyen JH, Menet C J Immunol. 2013 Oct 1;191(7):3568-77

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Characterization of immunologically active drugs in a novel organotypic co-culture model of the human gut and whole blood (2012) Schmohl M, Schneiderhan-Marra N, Baur N, Hefner K, Blum M, Stein GM, Joos TO, Schmolz M Int Immunopharmacol. 2012 Dec;14(4):722-8

A novel highly potent therapeutic antibody neutralizes multiple human chemokines and mimics viral immune modulation (2012) Scalley-Kim ML, Hess BW, Kelly RL, Krostag AR, Lustig KH, Marken JS, Ovendale PJ, Posey AR, Smolak PJ, Taylor JD, Wood CL, Bienvenue DL, Probst P, Salmon RA, Allison DS, Foy TM, Raport CJ PLoS One. 2012;7(8):e43332

A small animal peripheral challenge model of yellow fever using interferon-receptor deficient mice and the 17D-204 vaccine strain (2012) Thibodeaux BA, Garbinoa NC, Lissb NM, Piper J, Blair CD, Roehrig JT Vaccine

RN486, a Selective Bruton's Tyrosine Kinase Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis in Rodents (2012) Xu D, Kim Y, Postelnek J, Vu MD, Hu DQ, Liao C, Bradshaw M, Hsu J, Zhang J, Pashine A, Srinivasan D, Woods J, Levin A, O'Mahony A, Owens TD, Lou Y, Hill RJ, Narula S, Demartino J, Fine JS J Pharmacol Exp Ther. 2012 Apr;341(1):90-103

Bronchial and Bronchiolar Fibrosis in Rats Exposed to 2,3-Pentanedione Vapors: Implications for Bronchiolitis Obliterans in Humans (2012) Morgan DL, Jokinen MP, Price HC, Gwinn WM, Palmer SM, Flake GP Toxicol Pathol. 2012 Jan 3. [Epub ahead of print]

Evaluations of Tear Protein Markers in Dry Eye Disease: Repeatability of Measurement and Correlation with Disease (2012) Huang JF, Zhang Y, Rittenhouse KD, Pickering EH, McDowell MT Invest Ophthalmol Vis Sci. 2012 Jun 13. [Epub ahead of print]

Type I interferon and pattern recognition receptor signaling following particulate matter inhalation (2012) Erdely A, Antonini JM, Salmen-Muniz R, Liston A, Hulderman T, Simeonova PP, Kashon ML, Li S, Gu JK, Stone S, Chen BT, Frazer DG, Zeidler-Erdely PC Part Fibre Toxicol. 2012 Jul 9;9:25

Supernatants derived from chemotherapy-treated cancer cell lines can modify angiogenesis (2012) Liu WM, Dennis JL, Gravett AM, Chanthirakumar C, Kaminska E, Coulton G, Fowler DW, Bodman-Smith M, Dalgleish AG Br J Cancer. 2012 Jan 31 [Epub ahead of print]

Inflammation, organomegaly, and muscle wasting despite hyperphagia in a mouse model of burn cachexia (2012) Pedroso FE, Spalding PB, Cheung MC, Yang R, Gutierrez JC, Bonetto A, Zhan R, Chan HL, Namias N, Koniaris LG, Zimmers TA J Cachexia Sarcopenia Muscle. 2012 Mar 29

Characterization of AQX-1125, a small molecule SHIP1 activator Part 2. Efficacy studies in allergic and pulmonary inflammation models in vivo (2012) Stenton GR, Mackenzie LF, Tam P, Cross JL, Harwig C, Raymond J, Toews J, Chernoff D, Macrury T, Szabo C Br J Pharmacol. 2012 Nov 2

Immunomodulatory Effect of the Topical Ophthalmic Janus Kinase Inhibitor Tofacitinib (CP-690,550) in Patients with Dry Eye Disease (2012) Huang JF, Yafawi R, Zhang M, McDowell M, Rittenhouse KD, Sace F, Liew SH, Cooper SR, Pickering EH Ophthalmology. 2012 Jul;119(7):e43-50

Pharmacokinetics and Pharmacodynamics of Pegylated Interferon Lambda-1 in Cynomolgus Monkeys (2012) Byrnes-Blake KA, Pederson S, Klucher KM, Anderson-Haley M, Miller DM, Lopez-Talavera JC, Freeman JA J Interferon Cytokine Res. 2012 Jan 26. [Epub ahead of print]

Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival (2012) Walter S, Weinschenk T, Stenzl A, Zdrojowy R, Pluzanska A, Szczylik C, Staehler M, Brugger W, Dietrich PY, Mendrzyk R, Hilf N, Schoor O, Fritsche J, Mahr A, Maurer D, Vass V, Trautwein C, Lewandrowski P, Flohr C, Pohla H, Stanczak JJ, Bronte V, Mandruzzato S, Biedermann T, Pawelec G, Derhovanessian E, Yamagishi H, Miki T, Hongo F, Takaha N, Hirakawa K, Tanaka H, Stevanovic S, Frisch J, Mayer-Mokler A, Kirner A, Rammensee HG, Reinhardt C, Singh-Jasuja H Nat Med. 2012 Jul 29. doi: 10.1038/nm.2883. [Epub ahead of print]

Systemic Biomarkers of Neutrophilic Inflammation, Tissue Injury and Repair in COPD Patients with Differing Levels of Disease Severity (2012) Cockayne DA, Cheng DT, Waschki B, Sridhar S, Ravindran P, Hilton H, Kourteva G, Bitter H, Pillai SG, Visvanathan S, Müller KC, Holz O, Magnussen H, Watz H, Fine JS PLoS One. 2012;7(6):e38629

Systemic immunoregulatory and proteogenomic effects of tacrolimus to sirolimus conversion in liver transplant recipients (2012) Levitsky J, Mathew JM, Abecassis M, Tambur A, Leventhal J, Chandrasekaran D, Herrera N, Al-Saden P, Gallon L, Abdul-Nabi A, Yang GY, Kurian SM, Salomon DR, Miller J Hepatology. 2012 Jan 11. doi: 10.1002/hep.25579. [Epub ahead of print]

Highly aggregated antibody therapeutics can enhance the in vitro innate and late-stage T-cell immune responses (2012) Joubert MK, Hokom M, Eakin C, Zhou L, Deshpande M, Baker MP, Goletz TJ, Kerwin BA, Chirmule N, Narhi LO, Jawa V J Biol Chem. 2012 Jul 20;287(30):25266-79

Proteins involved in extracellular matrix dynamics are associated with respiratory syncytial virus disease severity (2012) Schuurhof A, Bont L, Hodemaekers HM, de Klerk A, de Groot H, Hofland RW, van de Pol AC, Kimpen JL, Janssen R Eur Respir J. 2012 Jun;39(6):1475-81

Altered lung function relates to inflammation in an acute LPS mouse model (2012) Håkansson HF, Smailag A, Brunmark C, Miller-Larsson A, Lal H Pulmonary Pharmacology & Therapeutics

Aging Exacerbates Obesity-Induced Oxidative Stress and Inflammation in Perivascular Adipose Tissue in Mice: A Paracrine Mechanism Contributing to Vascular Redox Dysregulation and Inflammation (2012) Bailey-Downs LC, Tucsek Z, Toth P, Sosnowska D, Gautam T, Sonntag WE, Csiszar A, Ungvari Z J Gerontol A Biol Sci Med Sci. 2012 Dec 3. [Epub ahead of print]

Neuroinflammatory phenotype in early Alzheimer's disease (2012) Sudduth TL, Schmitt FA, Nelson PT, Wilcock DM Neurobiol Aging. 2012 Oct 9. pii: S0197-4580(12)00468-X

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Peripheral profiling analysis for bipolar disorder reveals markers associated with reduced cell survival (2011) Herberth M, Koethe D, Levin Y, Schwarz E, Krzyszton ND, Schoeffmann S, Ruh H, Rahmoune H, Kranaster L, Schoenborn T, Leweke MF, Guest PC, Bahn S Proteomics 11: 94-105.

Pharmacological inhibition of myostatin suppresses systemic inflammation and muscle atrophy in mice with chronic kidney disease (2011) Zhang L, Rajan V, Lin E, Hu Z, Han HQ, Zhou X, Song Y, Min H, Wang X, Du J, Mitch WE FASEB J. 2011 May;25(5):1653-63

Discrimination of agonist and antagonist forms of CXCL10 in biologic samples (2011) Casrouge A, Bisiaux A, Stephen L, Schmolz M, Mapes J, Pfister C, Pol S, Mallet V, Albert ML Clin Exp Immunol. 2012 Jan;167(1):137-48

Modulation of Inflammatory and Lipoprotein Pathways in Skin and Serum from Patients with Psoriasis (2011) Faha NNM, Li K, Szapary PO, Krueger J, Brodmerkel C J Am Coll Cardiol; 57: 576

Identification of Systemic Markers from A Pulmonary Carbon Nanotube Exposure (2011) Erdely A, Liston A, Salmen-Muniz R, Hulderman T, Shih-Houng Y, Zeidler-Erdely PC, Castranova V, Simeonova PP Journal of Occupational & Environmental Medicine: June 2011 - Volume 53 - Issue - p S80–S86

Mark B. Coventry Award: Synovial C-reactive Protein: A Prospective Evaluation of a Molecular Marker for Periprosthetic Knee Joint Infection (2011) Parvizi J, Jacovides C, Adeli B, Jung KA, Hozack WJ Clin Orthop Relat Res. 2011 Jul 23. [Epub ahead of print]

Treatment of experimental anterior and intermediate uveitis by a dexamethasone intravitreal implant (2011) Ghosn CR, Li Y, Orilla WC, Lin T, Wheeler L, Burke JA, Robinson MR, Whitcup SM Invest Ophthalmol Vis Sci. 2011 May 2;52(6):2917-23

Deletion of a Malaria Invasion Gene Reduces Death and Anemia, in Model Hosts (2011) Gómez ND, Safeukui I, Adelani AA, Tewari R, Reddy JK, Rao S, Holder A, Buffet P, Mohandas N, Haldar K PLoS ONE 6(9): e25477

Molecular Markers for Diagnosis of Periprosthetic Joint Infection (2011) Jacovides CL, Parvizi J, Adeli B, Jung KA J Arthroplasty. 2011 May 12. [Epub ahead of print]

Relationship between pulmonary and systemic markers of exposure to multiple types of welding particulate matter (2011) Erdely A, Salmen-Muniz R, Liston A, Hulderman T, Zeidler-Erdely PC, Antonini JM, Simeonova PP Toxicology

Transmembrane tumour necrosis factor is neuroprotective and regulates experimental autoimmune encephalomyelitis via neuronal nuclear factor-kappaB (2011) Taoufik E, Tseveleki V, Chu SY, Tselios T, Karin M, Lassmann H, Szymkowski DE, Probert L Brain. 2011 Sep;134(Pt 9):2722-35

G-protein-coupled receptor GPR21 knockout mice display improved glucose tolerance and increased insulin response (2011) Gardner J, Wu S, Ling L, Danao J, Li Y, Yeh WC, Tian H, Baribault H Biochemical and Biophysical Research Communications

Type I Interferons increase host susceptibility to Trypanosoma cruzi infection (2011) Chessler AD, Caradonna KL, Da'dara A, Burleigh BA Infect Immun. 2011 Mar 14. [Epub ahead of print]

Human plasma inflammatory response during 5 days of exercise training in the heat (2011) Hailes WS, Slivka D, Cuddy J, Ruby BC Journal of Thermal Biology

Increased Disease Severity of Parasite-Infected TLR2-/- Mice Is Correlated with Decreased Central Nervous System Inflammation and Reduced Numbers of Cells with Alternatively Activated Macrophage Phenotypes in a Murine Model of Neurocysticercosis (2011) Gundra UM, Mishra BB, Wong K, Teale JM Infect Immun. 2011 Jul;79(7):2586-96

Treatment of experimental anterior and intermediate uveitis by a dexamethasone intravitreal implant (2011) Ghosn CR, Li Y, Orilla WC, Lin T, Wheeler L, Burke JA, Robinson MR, Whitcup SM Invest Ophthalmol Vis Sci. 2011 May 2;52(6):2917-23

Phagocytosis and digestion of pH-sensitive fluorescent dye (Eos-FP) transfected E. coli in whole blood assays from patients with severe sepsis and septic shock (2011) Schreiner L, Huber-Lang M, Weiss ME, Hohmann H, Schmolz M, Schneider EM J Cell Commun Signal. 2011 Jun;5(2):135-44
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Critical proinflammatory role of thymic stromal lymphopoietin and its receptor in experimental autoimmune arthritis (2011) Hartgring SA, Willis CR, Dean CE Jr, Broere F, van Eden W, Bijlsma JW, Lafeber FP, van Roon JA Arthritis Rheum. Jul;63(7):1878-87

Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during Experimental Autoimmune Encephalomyelitis (2011) Weinger JG, Brosnan CF, Loudig O, Goldberg MF, Macian F, Arnett HA, Prieto AL, Tsiperson V, Shafit-Zagardo B J Neuroinflammation. 2011 May 15;8:49

Inflammatory signaling in Alzheimer disease and depression (2011) Barber, R Cleveland Clinic Journal of Medicine vol. 78 Suppl 1 S47-S49
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Inflammatory profile and response to anti-TNF therapy in patients with chronic pulmonary sarcoidosis (2011) Loza MJ, Brodmerkel C, Du Bois RM, Judson MA, Costabel U, Drent M, Kavuru M, Flavin S, Lo KH, Barnathan ES, Baughman RP Clin Vaccine Immunol. 2011 Apr 20. [Epub ahead of print]

Validation of the Tetracycline Regulatable Gene Expression System for the Study of the Pathogenesis of Infectious Disease (2011) Chaturvedi AK, Lazzell AL, Saville SP, Wormley Jr.FL, Monteagudo C, Lopez-Ribot JL PLoS ONE 6(5): e20449

Rapidly Progressive, Fatal, Inhalation Anthraxlike Infection in a Human: Case Report, Pathogen Genome Sequencing, Pathology, and Coordinated Response (2011) Wright AM, Beres SB, Consamus EN, Long SW, Flores AR, Barrios R, Richter GS, Oh SY, Garufi G, Maier H, Drews AL, Stockbauer KE, Cernoch P, Schneewind O, Olsen RJ, Musser JM Arch Pathol Lab Med. 2011 Aug 9. [Epub ahead of print]

Molecular profiling and gene expression analysis in cutaneous sarcoidosis: The role of interleukin-12, interleukin-23, and the T-helper 17 pathway (2011) Judson MA, Marchell RM, Mascelli M, Piantone A, Barnathan ES, Petty KJ, Chen D, Fan H, Grund H, Ma K, Baribaud F, Brodmerkel C J Am Acad Dermatol. 2011 Sep 15. [Epub ahead of print]

Inhibition of RPE cell sterile inflammatory responses and endotoxin-induced uveitis by a cell-impermeable HSP90 inhibitor (2011) Qin S, Ni M, Wang X, Maurier-Mahé F, Shurland DL, Rodrigues GA Exp Eye Res. 2011 Oct 18. [Epub ahead of print]

Matrix Metalloproteinase-28 Deletion Amplifies Inflammatory and Extracellular Matrix Responses to Cardiac Aging (2011) Ma Y, Chiao YA, Zhang J, Manicone AM, Jin YF, Lindsey ML Microsc Microanal. 2011 Dec 8:1-10. [Epub ahead of print]

Features of sepsis caused by pulmonary infection with Francisella tularensis Type A strain (2011) Sharma J, Mares CA, Li Q, Morris EG, Teale JM Microb Pathog. 2011 Jul-Aug;51(1-2):39-47

Impaired resolution of inflammatory response in the lungs of JF1/Msf mice following carbon nanoparticle instillation (2011) Ganguly K, Upadhyay S, Irmler M, Takenaka S, Pukelsheim K, Beckers J, De Angelis MH, Hamelmann E, Stoeger T, Schulz H Respir Res. Jul 15;12(1):94

Serum markers associated with clinical improvement in patients with ankylosing spondylitis treated with golimumab (2011) Wagner C, Visvanathan S, Braun J, van der Heijde D, Deodhar A, Hsu B, Mack M, Elashoff M, Inman RD Ann Rheum Dis. 2011 Oct 28. [Epub ahead of print]
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Pathogenesis and Host Response in Syrian Hamsters following Intranasal Infection with Andes Virus (2011) Safronetz D, Zivcec M, LaCasse R, Feldmann F, Rosenke R, Long D, Haddock E, Brining D, Gardner D, Feldmann H, Ebihara H PLoS Pathog 7(12): e1002426

Effects of Echinaforce® treatment on ex vivo-stimulated blood cells (2011) Ritchie MR, Gertsch J, Klein P, Schoop R Phytomedicine. 2011 Jul 15;18(10):826-31
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Evidence for an antagonist form of the chemokine CXCL10 in patients chronically infected with HCV (2011) Casrouge A, Decalf J, Ahloulay M, Lababidi C, Mansour H, Vallet-Pichard A, Mallet V, Mottez E, Mapes J, Fontanet A, Pol S, Albert ML J Clin Invest. 121: 308-317.

A role for IL-27 in limiting T regulatory cell populations (2011) Wojno ED, Hosken N, Stumhofer JS, O'Hara AC, Mauldin E, Fang Q, Turka LA, Levin SD, Hunter CA J Immunol. 2011 Jul 1;187(1):266-73

Mycobacteria activate gamma delta T-cell anti-tumour responses via cytokines from type 1 myeloid dendritic cells: a mechanism of action for cancer immunotherapy (2011) Fowler DW, Copier J, Wilson N, Dalgleish AG, Bodman-Smith MD Cancer Immunol Immunother. 2011 Oct 15. [Epub ahead of print]

Cox-2 expression, PGE2 and cytokines production are inhibited by endogenously synthesized n-3 PUFAs in inflamed colon of fat-1 mice (2011) Gravaghi C, La Perle KM, Ogrodwski P, Kang JX, Quimby F, Lipkin M, Lamprecht SA J Nutr Biochem. 2011 Apr;22(4):360-5

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Attenuated Response of Aged Mice to Respiratory Francisella novicida Is Characterized by Reduced Cell Death and Absence of Subsequent Hypercytokinemia (2010) Mares CA, Sharma J, Ojeda SS, Li Q, Campos JA, Morris EG, Coalson JJ, Teale JM PLoS ONE 11: e14088.

Inflammatory and Hemostatic Response to Cardiopulmonary Bypass in Pediatric Population: Feasibility of Seriological Testing of Multiple Biomarkers (2010) Agirbasli M, Nguyen ML, Win K, Kunselman AR, Clark JB, Myers JL, Undar A Artif Organs. 34: 987-95.

Cardiovascular and inflammatory effects of intratracheally instilled ambient dust from Augsburg, Germany, in spontaneously hypertensive rats (SHRs) (2010) Upadhyay S, Ganguly K, Stoeger T, Semmler-Bhenke M, Takenaka S, Kreyling WG, Pitz M, Reitmeir P, Peters A, Eickelberg O, Wichmann HE, Schulz H Part Fibre Toxicol. 7: 27.

Quantitative Proteomic Plasma Profiling Reveals Activation of Host Defense to Oxidative Stress in Chronic SIV and Methamphetamine Comorbidity (2010) Pendyala G, Trauger SA, Siuzdak G, Fox HS AIDS Res Hum Retroviruses 2010 Oct 7. [Epub ahead of print]
Therapy Indications

Results of a phase I study in patients suffering from secondary-progressive multiple sclerosis demonstrating the safety of the amino acid copolymer PI-2301 and a possible induction of an anti-inflammatory cytokine response (2010) Kovalchin J, Krieger J, Genova M, Collins K, Augustyniak M, Masci A, Hittinger T, Kuca B, Edan G, Braudeau C, Rimbert M, Patel U, Mascioli E, Zanelli E J Neuroimmunol. 225: 153-63.

IL-1RL2 and Its Ligands Contribute to the Cytokine Network in Psoriasis (2010) Blumberg H, Dinh H, Dean C Jr, Trueblood ES, Bailey K, Shows D, Bhagavathula N, Aslam MN, Varani J, Towne JE, Sims JE J Immunol 185:4354-62.

Multiple sclerosis: Identification and clinical evaluation of novel CSF biomarkers (2010) Ottervald J, Franzén B, Nilsson K, Andersson LI, Khademi M, Eriksson B, Kjellström S, Marko-Varga G, Végvári A, Harris RA, Laurell T, Miliotis T, Matusevicius D, Salter H, Ferm M, Olsson T J Proteomics73: 1117-32.
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Limited Systemic Sclerosis Patients with Pulmonary Arterial Hypertension Show Biomarkers of Inflammation and Vascular Injury (2010) Pendergrass SA, Hayes E, Farina G, Lemaire R, Farber HW, Whitfield ML, Lafyatis R. PLoS ONE 5: e12106.

Lower Respiratory Tract Infection in Cynomolgus Macaques (Macaca fascicularis) Infected with Group A Streptococcus (2010) Olsen RJ, Ashraf M, Gonulal VE, Ayeras AA, Cantu C, Shea PR, Carroll RK, Humbird T, Greaver JL, Swain JL, Chang E, Ragasa W, Jenkins L, Lally KP, Blasdel T, Cagle P, Musser JM Microb Pathog 49: 336-47.

Evidence for Endotoxin Contamination in Plastic Na+-Heparin Blood Collection Tube Lots (2010) Newhall KJ, Diemer GS, Leshinsky N, Kerkof K, Chute HT, Russell CB, Rees W, Welcher AA, Patterson SD, Means GD Clin Chem 56: 1483-91.

Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality (2010) Marchlik E, Thakker P, Carlson T, Jiang Z, Ryan M, Marusic S, Goutagny N, Kuang W, Askew GR, Roberts V, Benoit S, Zhou T, Ling V, Pfeifer R, Stedman N, Fitzgerald KA, Lin LL, Hall JP J Leukoc Biol. 88: 1171-80.

In vivo and in vitro genetic evidence of involvement of neuregulin 1 in immune system dysregulation (2010) Marballi K, Quinones MP, Jimenez F, Escamilla MA, Raventós H, Soto-Bernardini MC, Ahuja SS, Walss-Bass C J Mol Med. 88: 1133-41.

Identification of distinct plasma biomarker signatures in patients with rapid and slow declining forms of COPD (2010) Devanarayan V, Scholand MB, Hoidal J, Leppert MF, Crackower MA, O'Neill GP, Gervais FG COPD 7: 51-58.

Hypercoagulability, platelet function, inflammation and coronary artery disease acuity: Results of the Thrombotic RIsk Progression (TRIP) Study. (2010) Tantry US, Bliden KP, Suarez TA, Kreutz RP, Dichiara J, Gurbel PA Platelets 21: 360-7.

Lack of a major role of Staphylococcus aureus Panton-Valentine leukocidin in lower respiratory tract infection in nonhuman primates. (2010) Olsen RJ, Kobayashi SD, Ayeras AA, Ashraf M, Graves SF, Ragasa W, Humbird T, Greaver JL, Cantu C, Swain JL, Jenkins L, Blasdel T, Cagle PT, Gardner DJ, DeLeo FR, Musser JM Am J Pathol 176: 1346-1354.

Insight in modulation of inflammation in response to diclofenac intervention: a human intervention study. (2010) van Erk MJ, Wopereis S, Rubingh C, van Vliet T, Verheij E, Cnubben NH, Pedersen TL, Newman JW, Smilde AK, van der Greef J, Hendriks HF, van Ommen B BMC Med Genomics 3: 5.

The transcriptome of Nrf2-/- mice provides evidence for impaired cell cycle progression in the development of cigarette smoke-induced emphysematous changes. (2010) Gebel S, Diehl S, Pype J, Friedrichs B, Weiler H, Schüller J, Xu H, Taguchi K, Yamamoto M, Müller T Toxicol Sci 115: 238-252.

Assessing changes in vascular permeability in a hamster model of viral hemorrhagic fever (2010) Gowen BB, Julander JG, London NR, Wong MH, Larson D, Morrey JD, Li DY, Bray M Virol J. 2010 Sep 16;7:240

Multi analyte profiling and variability of inflammatory markers in blood and induced sputum in patients with stable COPD (2010) Aaron SD, Vandemheen KL, Ramsay T, Zhang C, Avnur Z, Nikolcheva T, Quinn A Respir Res. 2010 Apr 22;11:41

Peripheral Blood Biomarkers Predict Disease Progression And Mortality In IPF (2010) Richards TJ, Lindell KO, Klesen M, Kaminski N, Zhang Y, Gibson KF Am J Respir Crit Care Me 181: A1120.

A Dual-Platform Proteomics Study of Plasma Biomarkers in Pediatric Patients Undergoing Cardiopulmonary Bypass. (2010) Umstead TM, Lu CJ, Freeman WM, Myers JL, Clark JB, Thomas NJ, Chinchilli VM, Vrana KE, Undar A, Phelps DS Pediatr Res 67: 641-9.

Interleukin-15 enhances proliferation and chemokine secretion of human follicular dendritic cells. (2010) Gil M, Park SJ, Chung YS, Park CS Immunology 130: 536-44.

Dysregulated macrophage-inflammatory protein-2 expression drives illness in bacterial superinfection of influenza. (2010) Zavitz CC, Bauer CM, Gaschler GJ, Fraser KM, Strieter RM, Hogaboam CM, Stampfli MR J Immunol 184: 2001-2013.

Comparative efficacy and safety of aliskiren and irbesartan in patients with hypertension and metabolic syndrome. (2010) Krone W, Hanefeld M, Meyer HF, Jung T, Bartlett M, Yeh CM, Rajman I, Prescott MF, Dole WP J Hum Hypertens [Epub ahead of print]

Aged mice display an altered pulmonary host response to Francisella tularensis live vaccine strain (LVS) infections (2010) Mares CA, Ojeda SS, Li Q, Morris EG, Coalson JJ, Teale JM Exp Gerontol. 45: 91-6.

Synthetic Ligands Against TLR2-9 in TruCulture - whole blood assays distinguish clinical stages of SIRS (trauma) and sepsis (2010) Bindja J, Weiss ME, Schmolz M, Stein GM, Mapes J, Schneiderhan-Marra N, Joos TO, Schneider EM TSIS Mar 9-13th
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Molecular Analyte Profiling of the Early Events and Tissue Conditioning Following Intravesical Bacillus Calmette-Guerin Therapy in Patients With Superficial Bladder Cancer. (2009) Bisiaux A, Thiounn N, Timsit MO, Eladaoui A, Chang HH, Mapes J, Mogenet A, Bresson JL, Prié D, Béchet S, Baron C, Sadorge C, Thomas S, Albert EB, Albert PS, Albert ML J Urol 181: 1571-1580.

Regression of Human Pancreatic Tumor Xenografts in Mice After a Single Systemic Injection of Recombinant Vaccinia Virus GLV-1h68. (2009) Yu YA, Galanis C, Woo Y, Chen N, Zhang Q, Fong Y, Szalay AA Mol Cancer Ther 8: 141-151.

CCR5 Expression Levels Influence NFAT Translocation, IL-2 Production, and Subsequent Signaling Events during T Lymphocyte Activation. (2009) Camargo JF, Quinones MP, Mummidi S, Srinivas S, Gaitan AA, Begum K, Jimenez F, VanCompernolle S, Unutmaz D, Ahuja SS, Ahuja SK J Immunol 182: 171-182.

Bacteria challenge in smoke-exposed mice exacerbates inflammation and skews the inflammatory profile (2009) Gaschler GJ, Skrtic M, Zavitz CC, Lindahl M, Onnervik PO, Murphy TF, Sethi S, Stämpfli MR. Am J Respir Crit Care Med. 179: 666-75.

Vaccination with an Attenuated Strain of Francisella novicida Prevents T-Cell Depletion and Protects Mice Infected with the Wild-Type Strain from Severe Sepsis. (2009) Sharma J, Li Q, Mishra BB, Georges MJ, Teale JM Infect Immun 77: 4314-4326.

Pathway focused protein profiling indicates differential function for IL-1B, -18 and VEGF during initiation and resolution of lung inflammation evoked by carbon nanoparticle exposure in mice (2009) Ganguly K, Upadhyay S, Irmler M, Takenaka S, Pukelsheim K, Beckers J, Hamelmann E, Schulz H, Stoeger T Part Fibre Toxicol. 6: 31.

Western-style diets induce oxidative stress and dysregulate immune responses in the colon in a mouse model of sporadic colon cancer (2009) Erdelyi I, Levenkova N, Lin EY, Pinto JT, Lipkin M, Quimby FW, Holt PR J Nutr. 139: 2072-8.

RIP4 Regulates Epidermal Differentiation and Cutaneous Inflammation. (2009) Rountree RB, Willis CR, Dinh H, Blumberg H, Bailey K, Dean C Jr, Peschon JJ, Holland PM J Invest Dermatol 130: 102-112.

Lethal Pulmonary Infection with Francisella Novicida is Associated with Severe Sepsis. (2009) Sharma J, Li Q, Mishra BB, Pena C, Teale JM J Leukoc Biol 86: 491-504.

RelB is differentially regulated by IkappaB Kinase-alpha in B cells and mouse lung by cigarette smoke (2009) Yang SR, Yao H, Rajendrasozhan S, Chung S, Edirisinghe I, Valvo S, Fromm G, McCabe MJ Jr, Sime PJ, Phipps RP, Li JD, Bulger M, Rahman I Am J Respir Cell Mol Biol 40: 147-158.

Pleural effects of indium phosphide in B6C3F1 mice: nonfibrous particulate induced pleural fibrosis (2009) Kirby PJ, Shines CJ, Taylor GJ, Bousquet RW, Price HC, Everitt JI, Morgan DL Exp Lung Res. 2009 Dec;35(10):858-82

Heterosubtypic anti-avian H5N1 influenza antibodies in intravenous immunoglobulins from globally separate populations protect against H5N1 infection in cell culture (2009) Sullivan JS, Selleck PW, Downton T, Boehm I, Axell AM, Ayob Y, Kapitza NM, Dyer W, Fitzgerald A, Walsh B, Lynch GW J Mol Genet Med 3: 217-224.

Strain-Dependent Increases in Retinal Inflammatory Proteins and Photoreceptor FGF-2 Expression in Streptozotocin-Induced Diabetic Rats. (2009) Kirwin SJ, Kanaly ST, Linke NA, Edelman JL Invest Ophthalmol Vis Sci 50: 5396-5404.

Muscular Dystrophy Therapy by Nonautologous Mesenchymal Stem Cells: Muscle Regeneration Without Immunosuppression and Inflammation. (2009) Shabbir A, Zisa D, Leiker M, Johnston C, Lin H, Lee T Transplantation 87: 1275-1282.

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Identification of transforming growth factor beta1-driven genetic programs of acute lung fibrosis. (2008) Pulichino AM, Wang IM, Caron A, Mortimer J, Auger A, Boie Y, Elias JA, Kartono A, Xu L, Menetski J, Sayegh CE Am J Respir Cell Mol Biol 39: 324-36.

Two distinct activation states of plasmacytoid dendritic cells induced by influenza virus and CpG 1826 oligonucleotide. (2008) Iparraguirre A, Tobias JW, Hensley SE, Masek KS, Cavanagh LL, Rendl M, Hunter CA, Ertl HC, von Andrian UH, Weninger W J Leukoc Biol 83: 610-620.

Tissue distribution and toxicity of intravenously administered titanium dioxide nanoparticles in rats. (2008) Fabian E, Landsiedel R, Ma-Hock L, Wiench K, Wohlleben W, van Ravenzwaay B Arch Toxicol 82: 151-157.

Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity. (2008) Demehri S, Liu Z, Lee J, Lin MH, Crosby SD, Roberts CJ, Grigsby PW, Miner JH, Farr AG, Kopan R PLoS Biol 6: e123.

Treatment of sepsis-induced acquired protein C deficiency reverses Angiotensin-converting enzyme-2 inhibition and decreases pulmonary inflammatory response. (2008) Richardson MA, Gupta A, O'Brien LA, Berg DT, Gerlitz B, Syed S, Sharma GR, Cramer MS, Heuer JG, Galbreath EJ, Grinnell BW J Pharmacol Exp Ther 325: 17-26.

Dexamethasone inhibits high glucose-, TNF-alpha-, and IL-1beta-induced secretion of inflammatory and angiogenic mediators from retinal microvascular pericytes. (2008) Nehmé A, Edelman J Invest Ophthalmol Vis Sci 49: 2030-2038.

Antiinflammatory and antiatherogenic effects of the NF-kappaB inhibitor acetyl-11-keto-beta-boswellic acid in LPS-challenged ApoE-/- mice. (2008) Cuaz-Pérolin C, Billiet L, Baugé E, Copin C, Scott-Algara D, Genze F, Büchele B, Syrovets T, Simmet T, Rouis M Arterioscler Thromb Vasc Biol 28: 272-277.

"Host Tissue Damage" Signal ATP Impairs IL-12 and IFNgamma Secretion in LPS Stimulated Whole Human Blood. (2008) Nalos M, Huang S, Sluyter R, Khan A, Santner-Nanan B, Nanan R, McLean AS Intensive Care Med 34: 1891-1897.
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Mechanisms of oncostatin M-induced pulmonary inflammation and fibrosis. (2008) Mozaffarian A, Brewer AW, Trueblood ES, Luzina IG, Todd NW, Atamas SP, Arnett HA J Immunol 181: 7243-7253.

MCP-1-deficient mice show reduced neuroinflammatory responses and increased peripheral inflammatory responses to peripheral endotoxin insult. (2008) Thompson WL, Karpus WJ, Van Eldik LJ J Neuroinflammation 5: 35.

Inhibition of integrin alpha(v)beta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosis. (2008) Puthawala K, Hadjiangelis N, Jacoby SC, Bayongan E, Zhao Z, Yang Z, Devitt ML, Horan GS, Weinreb PH, Lukashev ME, Violette SM, Grant KS, Colarossi C, Formenti SC, Munger JS Am J Respir Crit Care Med 177: 82-90.

Initial delay in the immune response to Francisella tularensis is followed by hypercytokinemia characteristic of severe sepsis and correlating with upregulation and release of damage-associated molecular patterns. (2008) Mares CA, Ojeda SS, Morris EG, Li Q, Teale JM Infect Immun 76: 3001-3010.

alpha causes chromatin modification on pro-inflammatory genes by cigarette smoke in mouse lung (2008) Yang SR, Valvo S, Yao H, Kode A, Rajendrasozhan S, Edirisinghe I, Caito S, Adenuga D, Henry R, Fromm G, Maggirwar S, Li JD, Bulger M, Rahman I. Am J Respir Cell Mol Biol. 2008 Jun;38(6):689-98

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Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging. (2007) Yang SR, Wright J, Bauter M, Seweryniak K, Kode A, Rahman I Am J Physiol Lung Cell Mol Physiol 292: L567-L576.

Eotaxin-1/CC chemokine ligand 11: a novel eosinophil survival factor secreted by human pulmonary artery endothelial cells (2007) Farahi N, Cowburn AS, Upton PD, Deighton J, Sobolewski A, Gherardi E, Morrell NW, Chilvers ER J Immunol. 2007 Jul 15;179(2):1264-73

Signal transducer and activator of transcription 3 signaling within hepatocytes attenuates systemic inflammatory response and lethality in septic mice. (2007) Sakamori R, Takehara T, Ohnishi C, Tatsumi T, Ohkawa K, Takeda K, Akira S, Hayashi N Hepatology 46: 1564-1573.

Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation. (2007) Blumberg H, Dinh H, Trueblood ES, Pretorius J, Kugler D, Weng N, Kanaly ST, Towne JE, Willis CR, Kuechle MK, Sims JE, Peschon JJ J Exp Med 204: 2603-2614.

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Characterization of the Inflammatory Response to a Highly Selective PDE4 Inhibitor in the Rat and the Identification of Biomarkers that Correlate with Toxicity. (2006) Dietsch GN, Dipalma CR, Eyre RJ, Pham TQ, Poole KM, Pefaur NB, Welch WD, Trueblood E, Kerns WD, Kanaly ST Toxicol Pathol 34: 39-51.

Fumaric acid esters are effective in chronic experimental autoimmune encephalomyelitis and suppress macrophage infiltration. (2006) Schilling S, Goelz S, Linker R, Luehder F, Gold R Clin Exp Immunol 145: 101-117.

Strain differences influence murine pulmonary responses to Stachybotrys chartarum. (2006) Rosenblum Lichtenstein JH, Molina RM, Donaghey TC, Brain JD Am J Respir Cell Mol Biol 35: 415-423.

Effects of cidofovir treatment on cytokine induction in murine models of cowpox and vaccinia virus infection. (2006) Knorr CW, Allen SD, Torres AR, Smee DF Antiviral Res 72: 125-133.

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Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity. (2005) Walmsley SR, Print C, Farahi N, Peyssonnaux C, Johnson RS, Cramer T, Sobolewski A, Condliffe AM, Cowburn AS, Johnson N, Chilvers ER J Exp Med 201: 105-115.

Multiplex proteomic approaches to sepsis research: case studies employing new technologies. (2005) Heuer JG, Cummins DJ, Edmonds BT Expert Rev Proteomics 2: 669-680.

Adoptive transfer of in vitro-stimulated CD4+CD25+ regulatory T cells increases bacterial clearance and improves survival in polymicrobial sepsis. (2005) Heuer JG, Zhang T, Zhao J, Ding C, Cramer M, Justen KL, Vonderfecht SL, Na S J Immunol 174: 7141-7146.

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Evaluation of protein C and other biomarkers as predictors of mortality in a rat cecal ligation and puncture model of sepsis. (2004) Heuer JG, Sharma GR, Gerlitz B, Zhang T, Bailey DL, Ding C, Berg DT, Perkins D, Stephens EJ, Holmes KC, Grubbs RL, Fynboe KA, Chen YF, Grinnell B, Jakubowski JA Crit Care Med 32: 1570-1578.

Simultaneous analysis of host and pathogen interactions during an in vivo infection reveals local induction of host acute phase response proteins, a novel bacterial stress response, and evidence of a host-imposed metal ion limited environment. (2004) Motley ST, Morrow BJ, Liu X, Dodge IL, Vitiello A, Ward CK, Shaw KJ Cell Microbiol 6: 849-865.

LXR-dependent gene expression is important for macrophage survival and the innate immune response. (2004) Joseph SB, Bradley MN, Castrillo A, Bruhn KW, Mak PA, Pei L, Hogenesch J, O'connell RM, Cheng G, Saez E, Miller JF, Tontonoz P Cell 119: 299-309.